/tools/Metallohydrolase_Enzyme_Design
Metallohydrolase_Enzyme_Design
baker-laboratory/Metallohydrolase_Enzyme_Design
20 stars4 forksJupyter NotebookAdded February 4, 2026
summary
This repository provides tutorials and pipelines for the computational design of metallohydrolases using the RFdiffusion2 model. It includes both dry lab data and wet lab data, facilitating the design and testing of enzyme sequences.
description
Official GitHub repository for the manuscript entitled "Computational Design of Metallohydrolases" by Kim, Woodbury, & Ahern et al. published in Nature. This notebook contains (1) tutorials on how to use RFdiffusion2 for enzyme design, (2) a demo pipeline for metallohydrolase design, and (3) data, sequences, and design models from the manuscript.
Ratings
N/A
0 ratings
Rate this tool: