/tools/ProtProfileMD

ProtProfileMD

finnlueth/ProtProfileMD

27 stars3 forksPythonAdded February 8, 2026
summary

ProtProfileMD is a tool that leverages protein dynamics to enhance homology detection by predicting per-residue distributions over structural representations. It utilizes a sequence-to-3D-probability model to capture the flexibility of proteins, improving the sensitivity of remote homology detection.

description

Protein Language Modeling beyond static folds reveals sequence-encoded flexibility

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