/tools/ProteinLM-TDG2-Mutation
ProteinLM-TDG2-Mutation
westlake-repl/ProteinLM-TDG2-Mutation
18 stars1 forksJupyter NotebookAdded February 8, 2026
summary
The ProteinLM-TDG2-Mutation repository provides code for optimizing a uracil-N-glycosylase variant using protein language models. It facilitates the generation of mutations and benchmarking of models in the context of programmable base editing.
description
Protein language models-assisted optimization of a uracil-N-glycosylase variant enables programmable T-to-G and T-to-C base editing
topics
base-editingcrispr-cas9enzymefitness-landscapelarge-languagellmmutationproteinprotein-engineeringdirect-evoluationdirect-evolutionlarge-langage-models
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