/tools/scFv_Pmpnn_AF2

scFv_Pmpnn_AF2

jbderoo/scFv_Pmpnn_AF2

GitHub
protein-designoptimizationtoolantibody
11 stars2 forksPythonWebsiteAdded February 4, 2026
summary

This tool provides a pipeline for designing and optimizing single chain variable fragment (scFv) antibodies targeting specific peptides and histone modifications. It automates the process of identifying CDR regions and optimizing antibody frameworks using AI models.

description

Associated code/pipeline for the publication "AI-assisted protein design to rapidly convert antibody sequences to intrabodies targeting diverse peptides and histone modifications"

topics

antibody-designantibody-optimizationantibody-sequenceantibody-structure-predictionhigh-throughput

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