/tools/LatentDE

LatentDE

HySonLab/LatentDE

37 stars2 forksPythonWebsiteAdded February 4, 2026
summary

LatentDE is a tool for protein sequence design that utilizes a latent-based directed evolution approach. It employs a variational autoencoder to optimize biological functionalities by exploring high-fitness mutants in the latent space, making it suitable for protein engineering tasks.

description

LatentDE: Latent-based Directed Evolution for Protein Sequence Design

topics

directed-evolutionevolutionary-algorithmgradient-ascentprotein-language-modelprotein-optimizationvariational-autoencoder

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